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Melanie Barrett, Psychiatrist

Melanie Barrett, MD, ABPN, Psychiatrist in Edmond, Oklahoma

Areas Of Focus:
Spravato/Esketamine
Ages Served
18-75+
Does Not Manage Medication
Provides therapy only
Accepts Insurance
Yes - View plans

About Melanie Barrett (She/Her)

Dr. Melanie Barrett received her medical degree from the University of Oklahoma College of Medicine following undergraduate studies in Psychology at Texas A&M University in College Station, Texas. She completed her psychiatry residency at the University of North Carolina Hospitals, Chapel Hill, where she served as Chief Resident. She maintains board certification through the American Board of Psychiatry & Neurology. Dr. Barrett specializes in interventional treatments including Zulresso (brexanolone) for postpartum depression as well as Spravato (esketamine) and ketamine IV therapy for treatment resistant depression. She regularly provides teaching and consultations to medical professionals interested in learning about postpartum depression and Zulresso.

Types of Care & Ages Served

Areas of Focus

Spravato/Esketamine

Specialty treatments include innovative, approved, and rapid-acting approaches for difficult-to-treat conditions.

Therapy Types

  • Specialty Service: TRD Spravato/Ketamine

Languages

  • English

Education

  • University of Oklahoma - Norman
  • Texas A&M University

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Frequently Asked Questions About Melanie Barrett

Please call us at 405-378-2727 to schedule an appointment with Melanie Barrett.

See what our patients are saying about Melanie Barrett

This was an amazing appt! And I have not been saying that about my Dr appts of late, especially regarding my new ADHD diagnosis. I’m late-diagnosed ADHD (this past summer, at age 51) and the struggle has been SO REAL to find an effective medication. My GP referred me to LifeStance for med management & so this was my 2nd appt here and the 1st with Dr. Barrett. (1st was with the PA, Skye Helker, with whom I was also impressed — I was just still maybe too “raw” to feel much hope from my appt with her 3 weeks ago.) After 7 months of defeat and crushed hope, I honestly did not think it possible to have hope on this issue restored until, and unless, a med started working. So for Dr. Barrett to even give me hope before meds was… mind blowing, to be honest. She listened & asked insightful questions. She was awesome. Plus, no one else has offered me ADHD coaching, and that issue was raised at both this, and the initial appointment. So… here’s to hope!
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Catherine P.

Catherine P.

Mar 21, 2025
Google Google
The first meeting ever with a doctor in her field of expertise. Sceptical of course, but she immediately set me at ease. Very easy to talk with, listens and repeats my questions so that we have understood each other completely. Have complete confidence in our relationship and her ability to solve my problems. Highly recommend her to everyone I have spoken with. Feels as if I'm talking with a true friend. My wife also feels as I do.
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Tom W.

Tom W.

Jan 05, 2017
Healthgrades Healthgrades
Dr Barrett is one of the rare Drs you find in psychiatry. She truly wants to listen and help you. She takes more than 5-10 minutes to hear what you’re going thru and works with you better than I’ve ever known, to make a plan to get you where you want to be. She is a life saver and someone who truly cares about her patients. If you need or want someone who knows what they’re doing and wants to help. GO SEE HER!!!
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Jeni

Jeni

Aug 28, 2018
Healthgrades Healthgrades
Dr. Barrett is amazing and I’m so grateful to have found her and the team at Lifestance in Edmond. She’s ultra-compassionate, supportive and is by far the most knowledgeable psychiatrist I’ve ever used. She’s a life saver, literally. Also, Jennifer Dunning, PA, is equally awesome. Together they have given me such excellent support and resources to be my strongest self.
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Laura G.

Laura G.

Jan 08, 2026
Google Google
I’ve been going here for a few months now and I have never felt more comfortable and welcomed by people before. The staff is always so kind and interested in what i have to say, and goes above and beyond to make sure patients feel comfortable. 100% recommend.
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Mya a.

Mya a.

Dec 10, 2024
Google Google
This office is amazing! Very responsive, comfortable and caring. The physicians listen and go over everything thoroughly to find the best treatment and explain what to expect. The nurses treat you like a good friend, so caring and comforting.
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Rachel L.

Rachel L.

Dec 18, 2023
Google Google
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Melanie Barrett, Psychiatrist in Edmond, Oklahoma

Melanie Barrett

Psychiatrist in Edmond, Oklahoma

New patient?

Check availability and book your first appointment Call for Availability

Already have an appointment?

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Articles by Melanie Barrett

Melanie Barrett is an expert medical reviewer at LifeStance Health.

Bulimia Nervosa
May 15, 2025 | CONDITION

Bulimia Nervosa

Bulimia nervosa is an eating disorder, commonly referred to simply as bulimia. It’s generally characterized by binge eating followed by purging.
Read more
PMS
Feb 28, 2022 | CONDITION

PMS

Extremely common, with most women of childbearing age experiencing at least one of the physical and/or psychological symptoms.
Read more
Premenstrual Dysphoric Disorder (PMDD)
Aug 05, 2022 | CONDITION

Premenstrual Dysphoric Disorder (PMDD)

PMDD is a very severe form of PMS that causes a range of emotional and physical symptoms that can make it difficult to function at...
Read more