This content has been updated from the previous article published on August 28, 2025. Globally, about 37 million people are affected by bipolar disorder ( World Health Organization, 2025 ). Living well with bipolar disorder goes beyond just addressing symptoms as they arise. Types of bipolar disorder can look different from person to person, making individualized care especially important. One of the most effective tools in preventing relapse and maintaining emotional stability is the consistent and appropriate use of prescribed evidence-based medications. This article explores current guidance on bipolar disorder medication, highlighting differences in treatments for mania versus depression, the role of maintenance therapy and what to consider about side effects. Matching Bipolar Disorder Medications to Different Phases Bipolar disorder often requires targeted treatment depending on whether an individual is experiencin...