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Jessica Burke, Nurse Practitioner

Jessica Burke, MSN, APRN, ANCC, Psychiatry in Greenville, South Carolina

Specialties:
Childhood behavioral issues School behavioral issues +82
Ages Served
3-75+
Manages Medications
Accepts Insurance

About Jessica Burke (She/Her)

Jessica Burke, PMHNP, helps patients in South Carolina achieve greater stability and improved quality of life through compassionate, evidence-based psychiatric care and medication management. As a prescriber at LifeStance Health, she partners with children, adolescents, teens, and adults to address a wide range of mental health conditions, including ADHD, anxiety, and depression, while offering additional support for other complex concerns. She is committed to creating a supportive, judgment-free environment where patients feel heard and empowered in their treatment journey. Jessica has a strong clinical interest in supporting individuals who have been recently discharged from a psychiatric hospital, helping them transition safely back into daily life with continuity of care, medication support, and ongoing monitoring. She understands the importance of this critical period and works closely with patients and families to reduce the risk of relapse, improve symptom management, and build sustainable routines that promote long-term stability. Her experience also includes working with diverse populations such as individuals with autism spectrum disorders, military members and veterans, and members of the LGBTQ+ community. Jessica provides medication management for conditions including mood disorders, substance use concerns, and childhood behavioral challenges, among others. Jessica earned her education from Walden University, Western Governors University, and Med Tech College, and has been practicing since 2020. She brings both clinical knowledge and a warm, approachable style to every patient interaction. Outside of her clinical work, Jessica enjoys spending time outdoors with her family as well as painting, diamond art, camping, and swimming.

Types of Care & Ages Served

Areas of Focus

Psychiatry/Medication Management

Treat and prevent mental health disorders using medication and therapy.

  • Childhood ADHD, attention or focus issues
  • Childhood behavioral issues
  • Eating issues: food deprivation
  • Eating issues: purging/regurgitating
  • School behavioral issues
  • Ability status
  • ADHD
  • Adoption & foster care
  • Aging
  • Alcohol use
  • Anger issues
  • Anxiety
  • Attachment issues
  • Autism spectrum & neurodivergence
  • Autism with developmental delay
  • Autism: requires some assistance
  • Bipolar Disorder
  • Body image
  • Bullying or harassment
  • Caregiving
  • Conditions caused by stress
  • Dementia & memory concerns
  • Depression/feeling down
  • Detachment/disconnection
  • Dissociative disorders
  • Domestic violence & abuse
  • Drug/substance use
  • Early adulthood: Independent living or relationships
  • Early adulthood: Starting college or career
  • Eating issues: binging
  • Emotional abuse
  • End-of-life challenges
  • Ethnic identity & mental health
  • Family conflict
  • Focus, concentration & memory
  • Gender affirming care evaluations
  • Gender identity & mental health
  • General relationship issues
  • Grief & loss
  • Hair pulling & skin picking
  • Hallucinations
  • Hoarding
  • Immigration/cultural status
  • Intellectual disability (caregiver-supported care)
  • Intellectual disability (living independently)
  • Intense mood changes
  • Learning challenges
  • LGBTQ+
  • Marital stress or divorce
  • Medical or surgical evaluations
  • Men's health/issues
  • Mental health changes after brain & head injuries
  • Mental health during perimenopause
  • Mental health related to pregnancy & reproductive health
  • Mental health support for chronic pain
  • Mental health support for neurological conditions
  • Mid-life transitions
  • Military, veteran, and first responder mental health
  • Obsessive Compulsive Disorder
  • Other addictive behaviors
  • Other women's health concerns
  • Panic attacks
  • Parenting
  • Patterns affecting behavior, emotions and relationships
  • Personality disorders & related conditions
  • Phobias
  • PMS & PMDD
  • Premarital counseling
  • Psychosis/issues with reality
  • Race, culture & mental health
  • Retirement
  • Schizophrenia/schizoaffective
  • School avoidance
  • Self-esteem
  • Self-injury or cutting
  • Sex & intimacy issues
  • Sexual trauma
  • Sleep issues or insomnia
  • Social skills & communication
  • Sports performance
  • Stress from ongoing health issues
  • Stress management
  • Stress related to discrimination & social injustice
  • Stroke-related mental health conditions
  • Trauma & PTSD
  • Unhealthy eating habits
  • Unusual thoughts or beliefs

Languages

  • English

Education

  • Walden University

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Frequently Asked Questions About Jessica Burke

Please use our online form to schedule an appointment with Jessica Burke. You can also call 864-823-6649 to have someone assist you.

See what our patients are saying about Jessica Burke

Jessica was amazing and such a relief to find! My journey to finding the right psychiatric care has been full of ups and downs, and at times it felt like going down one rabbit hole after another. Jessica truly listened and took the time to understand my needs. I felt heard, understood, and confident that she had my best interests at heart. Her knowledge and experience were evident in how she explained things and addressed my concerns. Finding someone who combines that expertise with compassion has been such a relief. I’m grateful to have found her and would highly recommend her!
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Labrisha W.

Labrisha W.

Oct 20, 2026
Google Google
This place is very helpful and very kind to me. Dr. Burke is frie n day and very good listener. She totally understood everything I talked about with her. I'm so happy and relieved that I have a doctor that knows and understands my illness.
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Donna P.

Donna P.

Aug 17, 2026
Google Google
I’ve felt seen and heard from NP Jessica Burke! Nothing but good things to say about her.
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Emma B.

Emma B.

Oct 19, 2026
Google Google
Great experience so far, love Jessica who definitely shed some light on my situation!!
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Jacquelina G.

Jacquelina G.

Sep 04, 2026
Google Google
I enjoy talking with PNP Burke. She is easy to talk to. Compassionate. Listens well.
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Nancy L.

Nancy L.

Oct 17, 2026
Google Google
I have a nice time with my Doctor Who was good to talk with she was very nice,
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Sarah S.

Sarah S.

Oct 09, 2026
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Jessica Burke, Psychiatry in Greenville, South Carolina

Jessica Burke

Psychiatry in Greenville, South Carolina

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